Angiotensin II down-regulates nephrin–Akt signaling and induces podocyte injury: role of c-Abl
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منابع مشابه
Angiotensin II down-regulates nephrin–Akt signaling and induces podocyte injury: roleof c-Abl
Recent studies have shown that nephrin plays a vital role in angiotensin II (Ang II)-induced podocyte injury and thus contributes to the onset of proteinuria and the progression of renal diseases, but its specific mechanism remains unclear. c-Abl is an SH2/SH3 domain-containing nonreceptor tyrosine kinase that is involved in cell survival and regulation of the cytoskeleton. Phosphorylated nephr...
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ژورنال
عنوان ژورنال: Molecular Biology of the Cell
سال: 2016
ISSN: 1059-1524,1939-4586
DOI: 10.1091/mbc.e15-04-0223